Closantel HCL API

About Closantel HCL API

Closantel HCl, or closantel hydrochloride, is a veterinary medication used primarily as an anthelmintic (anti-parasitic) agent in the treatment and prevention of parasitic infections in livestock. Here's an overview:

1. Function: Closantel acts by disrupting the metabolism and energy production of parasites, particularly trematodes (flukes) and nematodes (roundworms), leading to their paralysis and death. It is effective against a broad spectrum of parasitic species, including liver flukes, gastrointestinal worms, and lungworms, among others.

2. Indications: Closantel is used in veterinary medicine to treat and prevent parasitic infections in various livestock species, including cattle, sheep, goats, and sometimes in other animals such as horses and deer. It is particularly effective against liver flukes (Fasciola hepatica) and other fluke species that can cause significant damage to the liver and other organs in infected animals.

3. Administration: Closantel is typically administered orally as an oral drench or as an oral solution or suspension. The dosage and frequency of treatment depend on factors such as the type of parasite being targeted, the severity of the infection, and the species and weight of the animal being treated. It's essential to follow the dosage instructions provided by a veterinarian carefully.

4. Safety: Closantel is generally considered safe for use in livestock when administered at recommended dosages. However, it may cause side effects such as gastrointestinal upset, including diarrhea or vomiting, in some animals. Rare but more severe side effects may include neurological symptoms or allergic reactions. It's important to monitor animals closely during and after treatment and to report any adverse reactions to a veterinarian.

5. Regulation: Closantel is a prescription medication in many countries and should only be used under the guidance of a licensed veterinarian. It is important to follow all local regulations and guidelines regarding the use of closantel for the treatment and prevention of parasitic infections in livestock.

Pharmaceutical Grade Quality

Closantel HCL API ensures top-tier pharmaceutical standards by meeting stringent assay requirements (98%), low related substances (<0.5%), and heavy metals (<0.001%). Its compliance with standard reference identification and ICH guidelines provides reliable quality for veterinary applications.


Veterinary Use and Applications

Designed exclusively for veterinary use, Closantel HCL API is widely used to treat parasitic infestations in livestock. With a practically insoluble profile in water but good solubility in DMSO and DMF, it integrates smoothly into veterinary formulations, ensuring broad applicability and efficacy.


Secure Packaging and Storage

Closantel HCL API is packed in HDPE drums with double polythene liners for optimal protection. It should be stored below 25C, shielded from light and moisture, maintaining a stable shelf life of up to 36 months and preserving its pharmacological activity.