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Rosuvastatin Calcium is a medication commonly known by its brand name Crestor. It belongs to a class of drugs called statins, which are used to lower cholesterol levels in the blood and reduce the risk of cardiovascular events such as heart attacks and strokes. Here's an overview:
Function: Rosuvastatin works by inhibiting the enzyme HMG-CoA reductase, which plays a key role in the liver's production of cholesterol. By reducing cholesterol synthesis, rosuvastatin lowers levels of LDL cholesterol (often referred to as "bad" cholesterol) and triglycerides, while also modestly increasing levels of HDL cholesterol (the "good" cholesterol).
Indications: Rosuvastatin is prescribed primarily to treat high levels of cholesterol and triglycerides in the blood, particularly in individuals with conditions such as familial hypercholesterolemia or those at high risk of cardiovascular disease. It may also be used as part of a comprehensive treatment plan to reduce the risk of heart attacks, strokes, and other cardiovascular events.
Dosage: The typical starting dose of rosuvastatin is 5 to 10 mg once daily, although the dosage may be adjusted based on individual patient factors and response to treatment. Higher doses, up to a maximum of 40 mg per day, may be prescribed in some cases, particularly for patients with severe hypercholesterolemia or high cardiovascular risk.
Side Effects: While rosuvastatin is generally well-tolerated, it may cause side effects in some individuals. Common side effects may include headache, muscle aches or weakness, abdominal pain, nausea, and constipation. Rare but more serious side effects may include liver problems, muscle breakdown (rhabdomyolysis), and an increased risk of diabetes.
Safety Precautions: Rosuvastatin should be used with caution in certain populations, including individuals with liver or kidney disease, those with a history of muscle disorders or significant alcohol consumption, and pregnant or breastfeeding women. It's important for patients taking rosuvastatin to undergo regular monitoring of liver function and lipid levels, as well as to report any unusual symptoms to their healthcare provider.
Drug Interactions: Rosuvastatin may interact with other medications, including certain antibiotics, antifungal drugs, heart medications, and drugs used to treat HIV/AIDS. It's essential for patients to inform their healthcare provider about all medications, supplements, and herbal products they are taking to avoid potential interactions.